Rachel Brouwer

Contact Details

Neuroimaging Research Group 
University Medical Center Utrecht 
Heidelberglaan 100
3584 CX Utrecht
The Netherlands

Room: A.01.1.02

Tel: +31 (0)88 7557106
Fax: +31 (0)88 7555443
E-mail: r.m.brouwer-4@umcutrecht.nl

 

Research interests

* (Healthy) brain development and the influences of genes and environment on brain development (through the Brain SCALE project).
* Methodological issues in image processing and statistics

Publications

  • Brouwer RM, Mandl RCW, Schnack HG, van Soelen ILC, van Baal GC, Peper JS, Kahn RS, Boomsma DI, Hulshoff Pol HE, White matter development in early puberty: a longitudinal volumetric and diffusion tensor imaging twin study, PLoSONE, 7(4):e32316. Epub 2012 Apr 13. 
  • de Zeeuw P, Schnack HG, van Belle J, Weusten J, van Dijk S, Langen M, Brouwer RM, van Engeland H, Durston S. (2012), Differential brain development with low and high IQ in Attention-Deficit/Hyperactivity disorder, PLoS One 7(4):e35770. Epub 2012 Apr 20.
  • Hulshoff Pol HE, van Baal GC, Schnack HG, Brans RG, van der Schot AC, Brouwer RM, van Haren NE, Lepage C, Collins DL, Evans AC, Boomsma DI, Nolen W, Kahn RS (2012) Overlapping and segregating structural brain abnormalities in twins with schizophrenia or bipolar disorder. 
    Arch Gen Psychiatry. 2012 Apr;69(4):349-59.
  • van Soelen ILC, Brouwer RM, Peper JS, van Leeuwen M, Koenis MMG, van Beijsterveldt CEM, Swagerman SC, Kahn RS, Hulshoff Pol HE, Boomsma DI, Brain SCALE: Brain Structure and Cognition: an Adolescence Longitudinal twin study into Etiology, Twin Res Hum Genet, in press.
  • van Soelen ILC, Brouwer RM, van Baal GC, Schnack HG, Peper JS, Collins DL, Evans AC, Kahn RS, Boomsma DI, Pol HE (2012), Genetic influences on thinning of the cerebral cortex during development, NeuroImage, Feb 15;59(4):3871-80. Epub 2011 Dec 1.
  • van Soelen ILC, Brouwer RM, van Baal GCM, Schnack HG, Peper JS, Chen L, Kahn RS, Boomsma DI, Hulshoff Pol HE (2011). Heritability of volumetric brain changes and height in children entering puberty. Human Brain Mapping. Dec 3. doi: 10.1002/hbm.21468.
  • Boos HBM, Cahn W, van Haren NEM, Derks EM, Brouwer RM, Schnack HG, Hulshoff Pol HE, Kahn RS (2011), Focal and global brain measurements in siblings of patients with schizophrenia, Schizophrenia Bulletin 2011; doi: 
  • van Soelen IL, Brouwer RM, van Leeuwen M, Kahn RS, Hulshoff Pol HE, Boomsma DI (2011), Heritability of verbal and performance intelligence in a pediatric longitudinal sample, Twin Res Hum Genet, Apr;14(2):119-28.
  • Schnack HG, van Haren NE, Brouwer RM, van Baal GC, Picchioni M, Weisbrod M, Sauer H, Cannon TD, Huttunen M, Lepage C, Collins DL, Evans A, Murray RM, Kahn RS (2010), Mapping reliability in multicenter MRI: Voxel-based morphometry and cortical thickness, Hum Brain Mapp, Dec;31(12):1967-82.
  • van der Schot AC, Vonk R, Brouwer RM, van Baal GC, Brans RG, van Haren NE, Schnack HG, Boomsma DI, Nolen WA, Hulshoff Pol HE, Kahn RS (2010) Genetic and environmental influences on focal brain density in bipolar disorder, Brain. 2010 Oct;133(10):3080-92,Brain. Oct;133(10):3080-92.
  • Brouwer RM, Mandl RC, Peper JS, van Baal GC, Kahn RS, Boomsma DI, Hulshoff Pol HE (2010) Heritability of DTI and MTR in nine-year-old children. NeuroImage, Nov 15;53(3):1085-92.
  • van Soelen IL, Brouwer RM, Peper JS, van Beijsterveldt TC, van Leeuwen M, de Vries LS, Kahn RS, Hulshoff Pol HE, Boomsma DI (2010), Effects of gestational age and birth weight on brain volumes in healthy 9-year-old children, J Pediatr. 156, 896-901.
  • Brouwer RM, Hulshoff Pol HE, Schnack HG (2010) Segmentation of MRI brain scans using non-uniform partial volume densities. NeuroImage, Jan 1;49(1):467-77.
  • Peper JS, Brouwer RM, van LM, Schnack HG, Boomsma DI, Kahn RS, Hulshoff Pol HE (2010) HPG-axis hormones during puberty: a study on the association with hypothalamic and pituitary volumes. Psychoneuroendocrinology 35:133-140.
  • Peper JS, Brouwer RM, Schnack HG, van Baal GC, van LM, van den Berg SM, Delemarre van de Waal HA, Boomsma DI, Kahn RS, Hulshoff Pol HE (2009) Sex steroids and brain structure in pubertal boys and girls. Psychoneuroendocrinology 34:332-342.
  • Peper JS, Brouwer RM, van Baal GC, Schnack HG, van LM, Boomsma DI, Kahn RS, Hulshoff Pol HE (2009) Does having a twin brother make for a bigger brain? Eur J Endocrinol 160:739-746.
  • Peper JS, Schnack HG, Brouwer RM, van Baal GC, Pjetri E, Szekely E, van LM, van den Berg SM, Collins DL, Evans AC, Boomsma DI, Kahn RS, Hulshoff Pol HE (2009) Heritability of regional and global brain structure at the onset of puberty: a magnetic resonance imaging study in 9-year-old twin pairs. Hum Brain Mapp 30:2184-2196.
  • van Leeuwen M, Peper JS, van den Berg SM, Brouwer RM, Pol HEH, Kahn RS, Boomsma DI (2009) A genetic analysis of brain volumes and IQ in children. Intelligence 37:181-191.
  • Peper JS, Brouwer RM, Schnack HG, van Baal GC, van LM, van den Berg SM, Delemarrevande Waal HA, Janke AL, Collins DL, Evans AC, Boomsma DI, Kahn RS, Hulshoff Pol HE (2008) Cerebral white matter in early puberty is associated with luteinizing hormone concentrations. Psychoneuroendocrinology 33:909-915.
  • Peper JS, Brouwer RM, Boomsma DI, Kahn RS, Hulshoff Pol HE (2007) Genetic influences on human brain structure: a review of brain imaging studies in twins. Hum Brain Mapp 28:464-473.