Matthijs Bossong, PhD Department of Psychiatry, A01.126 University Medical Center Utrecht Heidelberglaan 100 3584 CX Utrecht The Netherlands phone: +31-88-75-56369 e-mail: m.bossong [at] umcutrecht.nl
Matthijs Bossong studied Biomedical Sciences at Utrecht University. After having completed his PhD in Utrecht on the role of the endocannabinoid system in human brain functions relevant for psychiatric disorders, he started his first postdoc position in September 2011 at the Institute of Psychiatry of King’s College London. Here, supported by an NWO Rubicon fellowship, Matthijs worked on two multimodal neuroimaging studies with people at an ultra-high risk for developing psychosis, one of them involving a treatment with the cannabinoid compound cannabidiol. In September 2014, he started his second postdoc at the Department of Psychiatry of the UMC Utrecht, where he has been coordinating a large European multi-centre study in which the potential of omega-3 fatty acids in the prevention of psychosis is examined in a large group of adolescent at-risk individuals. Supported by both an NWO Veni fellowship and a Rudolf Magnus Young Talent Fellowship, Matthijs is currently working as Assistant Professor on two Positron Emission Tomography (PET) studies investigating the neurobiological mechanisms underlying schizophrenia. One study examines the impact of cannabidiol treatment on microglia activity, whereas a second study focuses on synaptic density in the living brain of schizophrenia patients.
Iseger T.A., Bossong M.G. (2015) A systematic review of the antipsychotic properties of cannabidiol in humans. Schizophrenia Research 162 (1-3), 153 – 161.
Bossong M.G., Jansma J.M., Van Hell H.H., Jager G., Oudman E., Saliasi E., Kahn R.S., Ramsey N.F. (2012) Effects of Δ9-tetrahydrocannabinol on human working memory function. Biological Psychiatry 71 (8), 693 – 699.
Bossong M.G., Niesink R.J. (2010) Adolescent brain maturation, the endogenous cannabinoid system and cannabis-induced schizophrenia. Progress in Neurobiology 92 (3), 370 – 385.
Bossong M.G., Van Berckel B.N.M., Boellaard R., Zuurman L., Schuit R.C., Windhorst A.D., Van Gerven J.M.A., Ramsey N.F., Lammertsma A.A., Kahn R.S. (2009) ∆9-Tetrahydrocannabinol induces dopamine release in the human striatum. Neuropsychopharmacology 34 (3), 759 – 766.
Van Berckel B.N.M., Bossong M.G., Van Haaren N., Boellaard R., Comans E.F.I., Kloet R., Schuitemaker A., Caspers E., Luurtsema G., Windhorst A.D., Cahn W., Lammertsma A.A., Kahn R.S. (2008) Microglia activation in recent onset schizophrenia: a quantitative (R)-[11C]PK11195 PET study. Biological Psychiatry 64 (9), 820 – 822.